Referrals
Risk Management for Male BRCA1 or BRCA2 Mutation Carrier
These recommendations are for men who have NOT been affected by a relevant cancer. Individualised surveillance should be made for affected men based on their own post treatment plan.
| Cancer | BRCA1 mutation carrier risk to 70 yrs | BRCA2 mutation carrier risk to 70 yrs | BRCA2 mutation carrier risk to 70 yrs |
|---|---|---|---|
| Breast | 1.2% (0.22 – 2.8) |
~ 7% (3.2 – 12) |
<1% |
| Prostate | 8.6% | 15% | 5.9% |
| Melanoma | not increased | <5% | 2.5% |
| Pancreatic | risk may be increased | risk may be increased | <1% |
Pancreatic cancer risk is significantly associated with smoking
Breast Recommendations
Surveillance
Chest awareness and pectoral palpation on a regular basis
Risk Reducing Medications
No evidence
Risk Reducing Surgery
Not applicable
Prostate Recommendations
Surveillance
Consider annual PSA and digital rectal examination from early 40s
Pancreas Recommendations
Surveillance
- No evidence of benefit from surveillance
- Avoid smoking
Melanoma Recommendations
Surveillance
- Skin cancer awareness
- Avoid sun exposure and encourage liberal use of sun block
Referrals